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1

Activated human γδ T cells induce peptide-specific CD8+ T-cell responses to tumor-associated self-antigens

Bianca Altvater, Sibylle Pscherer, Silke Landmeier, Sareetha Kailayangiri, Barbara Savoldo, Heribert Juergens, Claudia Rossig

Journal:

Cancer Immunology, Immunotherapy

Year:

2012

Language:

english

File:

PDF, 570 KB

english, 2012

2

Safety and Persistence of Infused CD19-Car-Modified Multivirus Specific CTLs in B Cell Malignancies Post Allogeneic Hematopoietic Stem Cell Transplantation

C.R.Y. Cruz, K.P. Micklethwaite, B. Savoldo, S. Ku, R.A. Krance, O. Diouf, R. Kamble, A. Kennedy-Nasser, A.J. Barrett, E.J. Shpall, H.E. Heslop, C.M. Rooney, M.K. Brenner, C.M. Bollard, G. Dotti

Journal:

Biology of Blood and Marrow Transplantation

Year:

2012

Language:

english

File:

PDF, 60 KB

english, 2012

3

Giovanni Girolamo Savoldo's "Portrait of a Man with a Recorder"

Giovanni Girolamo Savoldo and H. Colin Slim

Journal:

Year:

1985

Language:

english

File:

PDF, 1.95 MB

english, 1985

4

Cord blood NK cells engineered to express IL-15 and a CD19-targeted CAR show long-term persistence and potent anti-tumor activity

Journal:

Year:

2017

Language:

english

File:

PDF, 6.17 MB

english, 2017

5

Eradication of neuroblastoma by T cells redirected with an optimized GD2-specific chimeric antigen receptor and interleukin-15

Chen, Yuhui, Sun, Chuang, Landoni, Elisa, Metelitsa, Leonid S, Dotti, Gianpietro, Savoldo, Barbara

Journal:

Clinical Cancer Research

Year:

2019

Language:

english

File:

PDF, 4.50 MB

english, 2019

6

GD2-specific CAR T cells encapsulated in an injectable hydrogel control retinoblastoma and preserve vision

Wang, Kai, Chen, Yuhui, Ahn, Sarah, Zheng, Min, Landoni, Elisa, Dotti, Gianpietro, Savoldo, Barbara, Han, Zongchao

Journal:

Year:

2020

File:

PDF, 7.58 MB

2020

7

Immunotherapy for Post-Transplant Lymphoproliferative Disease

Karin C. M. Straathof, Barbara Savoldo, Helen E. Heslop, Cliona M. Rooney

Journal:

British Journal of Haematology

Year:

2002

Language:

english

File:

PDF, 189 KB

english, 2002

8

Noninvasive Bioluminescent Imaging Demonstrates Long-Term Multilineage Engraftment of Ex Vivo-Expanded CD34-Selected Umbilical Cord Blood Cells

David Steiner, Juri Gelovani, Barbara Savoldo, Simon N. Robinson, William K. Decker, Nathalie Brouard, Amer Najjar, Dongxia Xing, Hong Yang, Sufang Li, Frank Marini, Patrick A. Zweidler-McKay, Catheri

Journal:

Year:

2009

Language:

english

File:

PDF, 1.14 MB

english, 2009

9

Use of cytokine polymorphisms and Epstein–Barr virus viral load to predict development of post-transplant lymphoproliferative disorder in paediatric liver transplant recipients

Timothy C. Lee, Barbara Savoldo, Neal R. Barshes, Cliona M. Rooney, Helen E. Heslop, Adrian P. Gee, Yvette Caldwell, Jaymee D. Scott, John A. Goss

Journal:

Clinical Transplantation

Year:

2006

Language:

english

File:

PDF, 88 KB

english, 2006

10

Quantification of a low cellular immune response to aid in identification of pediatric liver transplant recipients at high-risk for EBV infection

Timothy C. Lee, John A. Goss, Cliona M. Rooney, Helen E. Heslop, Neal R. Barshes, Yvette M. Caldwell, Adrian P. Gee, Jaymee D. Scott, Barbara Savoldo

Journal:

Clinical Transplantation

Year:

2006

Language:

english

File:

PDF, 108 KB

english, 2006

11

Selective elimination of a chemoresistant side population of B-CLL cells by cytotoxic T lymphocytes in subjects receiving an autologous hCD40L/IL-2 tumor vaccine

Heslop, H E, Foster, A E, Okur, F V, Biagi, E, Lu, A, Dotti, G, Yvon, E, Savoldo, B, Carrum, G, Goodell, M A

Journal:

Year:

2010

Language:

english

File:

PDF, 819 KB

english, 2010

12

Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety

Hoyos, V, Savoldo, B, Quintarelli, C, Mahendravada, A, Zhang, M, Vera, J, Heslop, H E, Rooney, C M, Brenner, M K, Dotti, G

Journal:

Year:

2010

Language:

english

File:

PDF, 979 KB

english, 2010

13

Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

Pule, Martin A, Savoldo, Barbara, Myers, G Doug, Rossig, Claudia, Russell, Heidi V, Dotti, Gianpietro, Huls, M Helen, Liu, Enli, Gee, Adrian P, Mei, Zhuyong

Journal:

Nature Medicine

Year:

2008

Language:

english

File:

PDF, 487 KB

english, 2008

14

Primitive hematopoietic progenitors within mobilized blood are spared by uncontrolled rate freezing

Cilloni, D, Garau, D, Regazzi, E, Sammarelli, G, Savoldo, B, Caramatti, C, Mangoni, L, Rizzoli, V, Carlo-Stella, C

Journal:

Bone Marrow Transplantation

Year:

1999

Language:

english

File:

PDF, 62 KB

english, 1999

15

Reverse transcription polymerase chain reaction is a reliable assay for detecting leukemic colonies generated by chronic myelogenous leukemia cells

Savoldo, B, Sammarelli, G, Dotti, G, Garau, D, Regazzi, E, Cilloni, D, Tabilio, A, Rizzoli, V, Carlo-Stella, C

Journal:

Year:

1998

Language:

english

File:

PDF, 75 KB

english, 1998

16

PPM1A and PPM1B act as IKKβ phosphatases to terminate TNFα-induced IKKβ-NF-κB activation

Wenjing Sun, Yang Yu, Gianpietro Dotti, Tao Shen, Xiaojie Tan, Barbara Savoldo, Amy K. Pass, Meijin Chu, Dekai Zhang, Xiongbin Lu, Songbin Fu, Xia Lin, Jianhua Yang

Journal:

Cellular Signalling

Year:

2009

Language:

english

File:

PDF, 486 KB

english, 2009

17

Human antibody titers to Epstein–Barr Virus (EBV) gp350 correlate with neutralization of infectivity better than antibody titers to EBV gp42 using a rapid flow cytometry-based EBV neutralization assay

Junji Sashihara, Peter D. Burbelo, Barbara Savoldo, Theodore C. Pierson, Jeffrey I. Cohen

Journal:

Year:

2009

Language:

english

File:

PDF, 706 KB

english, 2009

18

Adenovector-induced expression of human-CD40-ligand (hCD40L) by multiple myeloma cells: A model for immunotherapy

Gianpietro Dotti, Barbara Savoldo, Satoshi Takahashi, Tatiana Goltsova, Michael Brown, Donna Rill, Cliona Rooney, Malcolm Brenner

Journal:

Experimental Hematology

Year:

2001

Language:

english

File:

PDF, 194 KB

english, 2001

19

Cellular Immunity to Epstein-Barr Virus in Liver Transplant Recipients Treated with Rituximab for Post-Transplant Lymphoproliferative Disease

Barbara Savoldo, Cliona M. Rooney, Ruben E. Quiros-Tejeira, Yvette Caldwell, Hans-Joachim Wagner, Timothy Lee, Milton J. Finegold, Gianpietro Dotti, Helen E. Heslop, John A. Goss

Journal:

American Journal of Transplantation

Year:

2005

Language:

english

File:

PDF, 140 KB

english, 2005

20

Quantitative EBV Viral Loads and Immunosuppression Alterations can Decrease PTLD Incidence in Pediatric Liver Transplant Recipients

Timothy C. Lee, Barbara Savoldo, Cliona M. Rooney, Helen E. Heslop, Adrian P. Gee, Yvette Caldwell, Neal R. Barshes, Jaymee D. Scott, Lisa J. Bristow, Christine A. O'Mahony, John A. Goss

Journal:

American Journal of Transplantation

Year:

2005

Language:

english

File:

PDF, 120 KB

english, 2005

21

55: T-cells Redirected Against CD70 for the Immunotherapy of Hematological Malignancies

D. Shaffer, B. Savoldo, G. Dotti, D. Spencer, S. Kenney, C.M. Rooney, S. Gottschalk

Journal:

Biology of Blood and Marrow Transplantation

Year:

2008

Language:

english

File:

PDF, 57 KB

english, 2008

22

Cytotoxic T Lymphocytes (CTL) Specific for Adenovirus and CMV Can Be Generated From Umbilical Cord Blood for Adoptive Immunotherapy

P. Hanley, B. Savoldo, C.R. Cruz, A.M. Leen, J.J. Molldrem, H. Liu, A.P. Gee, H.E. Heslop, G. Dotti, E.J. Shpall, C.M. Bollard

Journal:

Biology of Blood and Marrow Transplantation

Year:

2009

Language:

english

File:

PDF, 89 KB

english, 2009

23

Engineering CD19-Redirected T Lymphocytes to Enhance Their Safety and Efficacy

V. Hoyos, B. Savoldo, J.F. Vera, C. Quintarelli, H. Heslop, C.M. Rooney, M.K. Brenner, G. Dotti

Journal:

Biology of Blood and Marrow Transplantation

Year:

2009

Language:

english

File:

PDF, 49 KB

english, 2009

24

Treatment of High-Risk Neuroblastoma with Adoptively Transferred T Lymphocytes Genetically Engineered to Recognize GD2

C.U. Louis, M.A. Pule, B. Savoldo, G.D. Myers, C. Rossig, H.V. Russell, G. Dotti, M.H. Huls, E. Liu, A. Gee, Z. Mei, E. Yvon, H.L. Weiss, C.M. Rooney, H.E. Heslop, M.K. Brenner

Journal:

Biology of Blood and Marrow Transplantation

Year:

2009

Language:

english

File:

PDF, 66 KB

english, 2009

25

Genetic Modification of Antigen-Specific Cytotoxic T Lymphocytes (CTLS) Restores Their Ability to Respond to Interleukin-7 (IL-7)

J.F. Vera, V. Hoyos, B. Savoldo, C. Quintarelli, G. Attianese Greta, A.M. Leen, H. Liu, A.E. Foster, H.E. Heslop, C.M. Rooney, M.K. Brenner, G. Dotti

Journal:

Biology of Blood and Marrow Transplantation

Year:

2009

Language:

english

File:

PDF, 57 KB

english, 2009

26

Monoculture-Derived Leukemia and Multivirus Specific Cytotoxic T-Lymphocytes for Immunotherapy of All in Hematopoietic Stem Cell and Umbilical Cord Blood Transplants

K.P. Micklethwaite, B. Savoldo, L.J. Cooper, E.J. Schpall, C.M. Rooney, H.E. Heslop, M.K. Brenner, C.M. Bollard, G. Dotti

Journal:

Biology of Blood and Marrow Transplantation

Year:

2009

Language:

english

File:

PDF, 81 KB

english, 2009

27

Polyclonal Prame-Specific Cytotoxic T Lymphocytes Generated Using Protein-Spanning Pools of Overlapping Pentadecapeptides Target Chronic Myeloid Leukemia

C. Quintarelli, G. Dotti, B. De Angelis, V. Hoyos, F. Pane, M. Mims, H. Heslop, C.M. Rooney, M.K. Brenner, B. Savoldo

Journal:

Biology of Blood and Marrow Transplantation

Year:

2009

Language:

english

File:

PDF, 72 KB

english, 2009

28

Expansion Of Regulatory T Cells With Ultra Low-Dose Il-2 After Allogeneic Hematopoietic Stem Cell Transplantation

A.A. Kennedy-Nasser, S. Ku, W. Chaiyarat, A. Foster, B. Savoldo, E. Yvon, K.S. Leung, G. Carrum, R.T. Kamble, H.E. Heslop, M.K. Brenner, R.A. Krance, C.M. Bollard

Journal:

Biology of Blood and Marrow Transplantation

Year:

2009

Language:

english

File:

PDF, 45 KB

english, 2009

29

Cytotoxic T Lymphocytes (CTL) Specific For CMV, Adenovirus, And EBV Can Be Generated From Naive T Cells For Adoptive Immunotherapy

P. Hanley, B. Savoldo, C.R. Cruz, A.M. Leen, J. Rodgers, H. Liu, A.P. Gee, H.E. Heslop, C.M. Rooney, M.K. Brenner, E.J. Shpall, C.M. Bollard

Journal:

Biology of Blood and Marrow Transplantation

Year:

2010

Language:

english

File:

PDF, 56 KB

english, 2010

30

The Clinical Use of Cord Blood-Derived Virus-Specific Cytotoxic T Lymphocytes Reactive Against Cytomegalovirus (CMV), Adenovirus, and Epstein-Barr Virus (EBV)

P.J. Hanley, C. Martinez, K. Leung, C.R.Y. Cruz, B. Savoldo, A.M. Leen, G. Dotti, H. Liu, A.P. Gee, C.M. Rooney, R.A. Krance, H.E. Heslop, E.J. Shpall, C.M. Bollard

Journal:

Biology of Blood and Marrow Transplantation

Year:

2011

Language:

english

File:

PDF, 60 KB

english, 2011

31

Effect of a Co-Stimulatory Endodomain on the Performance of T Cells Expressing a Chimeric Antigen Receptor Directed at CD19 in Patients With Relapsed/Refractory B-Cell Malignancies

C.A. Ramos, B. Savoldo, E. Liu, C.M. Bollard, G. Carrum, R.T. Kamble, M.P. Mims, M. Keating, A.P. Gee, Z. Mei, C.M. Rooney, H.E. Heslop, M.K. Brenner, G. Dotti

Journal:

Biology of Blood and Marrow Transplantation

Year:

2011

Language:

english

File:

PDF, 88 KB

english, 2011

32

NaïVe T Cells From Cord Blood and CMV-Seronegative Donors Recognize Atypical Epitopes of Cmvpp65 and Can Be Used for Adoptive Immunotherapy

P.J. Hanley, S. Lam, C.R.Y. Cruz, B. Savoldo, T. Benjamin, K. Stephanie, D. Lilleri, G. Gerna, G. Demmler-Harrison, G. Dotti, H.E. Heslop, M.K. Brenner, C.M. Rooney, E.J. Shpall, J.R. Rodgers, C.M. Bo

Journal:

Biology of Blood and Marrow Transplantation

Year:

2011

Language:

english

File:

PDF, 66 KB

english, 2011

33

Human Papillomavirus Type 16 (HPV16) E6/E7-Specific Cytotoxic T Lymphocytes (CTLs) for Immunotherapy of HPV-Associated Malignancies

C.A. Ramos, N. Narala, A.M. Leen, U. Gerdemann, M.L. Anderson, E.M. Sturgis, B. Savoldo, H.E. Heslop, M.K. Brenner, C.M. Rooney

Journal:

Biology of Blood and Marrow Transplantation

Year:

2012

Language:

english

File:

PDF, 57 KB

english, 2012

34

Ultra Low-Dose Il-2 Mediated Expansion of Regulatory T Cells as GVHD Prophylaxis for Recipients of Allogeneic Hematopoietic Stem Cells

A.A. Kennedy-Nasser, S. Ku, J. Melenhorst, J. Barrett, Y. Hazrat, A.G. Durett, A. Foster, B. Savoldo, E. Yvon, H.E. Heslop, G. Carrum, R.T. Kamble, M.K. Brenner, R.A. Krance, C.M. Bollard

Journal:

Biology of Blood and Marrow Transplantation

Year:

2012

Language:

english

File:

PDF, 56 KB

english, 2012

35

Late donor cardiectomy after paediatric heterotopic cardiac transplantation

V Tsang, M Yacoub, S Sridharan, M Burch, R Radley-Smith, A Khaghani, B Savoldo, PJ Amrolia

Journal:

Year:

2009

Language:

english

File:

PDF, 884 KB

english, 2009

36

Interleukin 15 Provides Relief to CTLs from Regulatory T Cell-Mediated Inhibition: Implications for Adoptive T Cell-Based Therapies for Lymphoma

Perna, S. K., De Angelis, B., Pagliara, D., Hasan, S. T., Zhang, L., Mahendravada, A., Heslop, H. E., Brenner, M. K., Rooney, C. M., Dotti, G., Savoldo, B.

Journal:

Clinical Cancer Research

Year:

2013

Language:

english

File:

PDF, 1.02 MB

english, 2013

37

Generation Of Virus-Specific Cytotoxic T Lymphocytes (CTLS) Resistant to the Immunosuppressive Drug Tacrolimus (FK506)

B. De Angelis, G. Dotti, C. Quintarelli, L.E. Huye, L. Zhang, M. Zhang, H.E. Heslop, M.K. Brenner, C.M. Rooney, B. Savoldo

Journal:

Biology of Blood and Marrow Transplantation

Year:

2009

Language:

english

File:

PDF, 57 KB

english, 2009

38

Cellular therapy of Epstein–Barr-virus-associated post-transplant lymphoproliferative disease

Helen E. Heslop, Barbara Savoldo, Cliona M. Rooney

Journal:

Best Practice & Research Clinical Haematology

Year:

2004

Language:

english

File:

PDF, 130 KB

english, 2004

39

300 A novel immunotherapy approach for B-CLL by use of Chimeric TCR

G. Giordano Attianese, V. Hoyos, V. Marin, B. Savoldo, I. Pizzitola, V. Agostoni, M. Parma, A. Biondi, G. Dotti, E. Biagi

Journal:

European Journal of Cancer Supplements

Year:

2010

Language:

english

File:

PDF, 69 KB

english, 2010

40

Selective depletion of a minor subpopulation of B-chronic lymphocytic leukemia cells is followed by a delayed but progressive loss of bulk tumor cells and disease regression

Aaron E Foster, Fatma V Okur, Ettore Biagi, An Lu, Gianpietro Dotti, Eric Yvon, Barbara Savoldo, George Carrum, Michael Andreeff, Margaret A Goodell, Helen E Heslop, Malcolm K Brenner

Journal:

Molecular Cancer

Year:

2009

Language:

english

File:

PDF, 1.02 MB

english, 2009

41

Generation of multi-leukemia antigen-specific T cells to enhance the graft-versus-leukemia effect after allogeneic stem cell transplant

Weber, G, Gerdemann, U, Caruana, I, Savoldo, B, Hensel, N F, Rabin, K R, Shpall, E J, Melenhorst, J J, Leen, A M, Barrett, A J, Bollard, C M

Journal:

Year:

2013

Language:

english

File:

PDF, 824 KB

english, 2013

42

Chimeric antigen receptors (CARs) from bench-to-bedside

Savoldo, Barbara, Dotti, Gianpietro

Journal:

Immunology Letters

Year:

2013

Language:

english

File:

PDF, 409 KB

english, 2013

43

T Lymphocytes Redirected against the Chondroitin Sulfate Proteoglycan-4 Control the Growth of Multiple Solid Tumors both In Vitro and In Vivo

Geldres, C., Savoldo, B., Hoyos, V., Caruana, I., Zhang, M., Yvon, E., Del Vecchio, M., Creighton, C. J., Ittmann, M., Ferrone, S., Dotti, G.

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.47 MB

english, 2014

44

Ultra Low-Dose IL-2 for GVHD Prophylaxis after Allogeneic Hematopoietic Stem Cell Transplantation Mediates Expansion of Regulatory T Cells without Diminishing Antiviral and Antileukemic Activity

Kennedy-Nasser, A. A., Ku, S., Castillo-Caro, P., Hazrat, Y., Wu, M.-F., Liu, H., Melenhorst, J., Barrett, A. J., Ito, S., Foster, A., Savoldo, B., Yvon, E., Carrum, G., Ramos, C. A., Krance, R. A., L

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 976 KB

english, 2014

45

Program of the American Dairy Science Association Southern Division

Louis, C.U., Savoldo, B., Heczey, A., Yvon, E., Gee, A., Rooney, C., Heslop, H., Dotti, G., Brenner, M.K.

Journal:

Journal of Dairy Science

Year:

1973

Language:

english

File:

PDF, 452 KB

english, 1973

46

Generation and administration of autologous T cells transduced with a 3rd generation GD2 chimeric antigen receptor for patients with relapsed or refractory neuroblastoma

Louis, C.U., Savoldo, B., Heczey, A., Yvon, E., Gee, A., Rooney, C., Heslop, H., Dotti, G., Brenner, M.K.

Journal:

Year:

2014

Language:

english

File:

PDF, 78 KB

english, 2014

47

Clinical Responses in Patients Infused with T Lymphocytes Redirected to Target Kappa-Light Immunoglobulin Chain

Ramos, Carlos A., Savoldo, Barbara, Liu, Enli, Gee, Adrian P., Mei, Zhuyong, Grilley, Bambi, Rooney, Cliona M., Heslop, Helen E., Brenner, Malcolm K., Dotti, Gianpietro

Journal:

Biology of Blood and Marrow Transplantation

Year:

2014

Language:

english

File:

PDF, 153 KB

english, 2014

48

Fucosylation with fucosyltransferase VI or fucosyltransferase VII improves cord blood engraftment

Robinson, Simon N., Thomas, Michael W., Simmons, Paul J., Lu, Junjun, Yang, Hong, Parmar, Simrit, Liu, Xiaoying, Shah, Nina, Martín-Antonio, Beatriz, Bollard, Catherine, Dotti, Gianpietro, Savoldo, Ba

Journal:

Year:

2014

Language:

english

File:

PDF, 452 KB

english, 2014

49

Adverse events following infusion of T cells for adoptive immunotherapy: a 10-year experience

Cruz, Conrad Russell, Hanley, Patrick J., Liu, Hao, Torrano, Vicky, Lin, Yu-Feng, Arce, James A., Gottschalk, Stephen, Savoldo, Barbara, Dotti, Gianpietro, Louis, Chrystal U., Leen, Ann M., Gee, Adria

Journal:

Year:

2010

Language:

english

File:

PDF, 131 KB

english, 2010

50

Extending the Option of CMV-Specific T Cells from the CMV-Seronegative Donor

Hanley, Patrick J., Nikiforow, Sarah, Melenhorst, Jan, Scheinberg, Phillip, Savoldo, Barbara, Dotti, Gianpietro, Rooney, Cliona M., Heslop, Helen E., Shpall, Elizabeth J., Barrett, A. John, Bollard, C

Journal:

Biology of Blood and Marrow Transplantation

Year:

2014

Language:

english

File:

PDF, 53 KB

english, 2014

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